Linebacker De’Vondre Campbell’s refusal to play in the 49ers’ loss Thursday night will result in his termination from the ...

Los Angeles Rams wide receiver Puka Nacua (17) reacts after catching a pass against the San Francisco 49ers during the second ...

It’s one of the best games of the year and it’s one of two matchups on the weekend that could be a potential Super Bowl ...

ET, two of the best offensive performers in the NFL will be on show when George Kittle and the San Francisco 49ers host Kyren ...

Cornerback Rasul Douglas has already been ruled out with a knee injury. Douglas did not practice all week after suffering the ...

Buffalo Bills quarterback Josh Allen received massive praise from Detroit Lions coach Dan Campbell before their matchup.

The Bills had their lengthy winning streak snapped last Sunday, and they'll now look to do the same to the Lions in Week 15.

The Bills are rebounding from an exhausting 44-42 loss to the Los Angeles Rams in which Josh Allen accounted for 424 total yards and six touchdowns. This defeat ceased the seven-game win streak the ...

TNF matchup between the 49ers and Rams, they reached an all-time low not seen since the 1922 Dayton Triangles.

The Buffalo Bills are seeking to bounce back from one of the worst defensive performances of the Sean McDermott era and they ...

When the schedule was released during the offseason, many football fans circled this game on the calendar. The Bills take on ...

Dallas Cowboys (5-8) at Carolina Panthers (3-10) 1 p.m. ET, FOX What are the odds the Carolina Panthers are favorites in a ...