Our fantasy football buzz file, with contributions from our ESPN fantasy writers and our NFL Nation reporters, aims to ...

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

Welcome to Week 15 of the NFL season, a week that is synonymous with the start of Fantasy football postseasons. Fortunately ...

San Francisco 49ers rookie running back Isaac Guerendo (foot) is officially active for Thursday night's divisional clash in ...

Micah Roberts, on a 26-6 run on 49ers picks, has revealed his Week 15 Thursday Night Football expert picks for Los Angeles vs ...

The Los Angeles Rams and San Francisco 49ers square off on "Thursday Night Football" to start Week 15 of the NFL season. Of ...

I just feel like I had a lot of plays left out there that I could have made for our team,” Brock Purdy said. “I thought the ...

Head coach Kyle Shanahan shared injury updates on LB Dre Greenlaw and S Ji'Ayir Brown and recapped the team's 12-6 loss to the Los Angeles Rams.

"GMFB" share their thoughts on the San Francisco 49ers linebacker De'Vondre Campbell walking off field during game.

Before the positive news, the 49ers announced six inactive players for Thursday night, including All-Pro left tackle Trent ...

The Los Angeles Rams and San Francisco 49ers kept their playoff aspirations alive in Week 14 with massive victories. However, the NFC West foes bump into each o ...