San Francisco 49ers QB Brock Purdy, LB Fred Warner, TE George Kittle, DL Nick Bosa and LB Dre Greenlaw outlined the team's ...

Los Angeles Rams outside linebacker Byron Young engulfs San Francisco 49ers running back Isaac Guerendo on an authoritative tackle for a loss in the rain.

No one could have expected the San Francisco 49ers to be in this position so late into the 2024 season. The 49ers are 6-7 on the year, sitting tied for last pla ...

Deebo Samuel after his rough outing included tackling his own teammate, bad stats and dropping an easy touchdown.

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

The Los Angeles Rams and San Francisco 49ers square off on "Thursday Night Football" to start Week 15 of the NFL season. Of ...

Micah Roberts, on a 26-6 run on 49ers picks, has revealed his Week 15 Thursday Night Football expert picks for Los Angeles vs ...

The San Francisco 49ers are about an hour and a half away from taking on the Los Angeles Rams, and the inactive list is out.

The 49ers will have defensive lineman Nick Bosa, linebacker Dre Greenlaw and running back Isaac Guerendo for Thursday Night Football.

Neither will be eliminated from playoff contention with a loss, but it would be devastating for their 2024 playoff chances.

Guerendo (foot) is listed as active Thursday against the Rams, Lindsey Pallares of the 49ers' official site reports. Guerendo came out of this past Sunday's win versus the Bears with a sprained foot, ...

Running back Isaac Guerendo is officially active for the the 49ers' pivotal "Thursday Night Football" game against the Los Angeles Rams despite dealing with a foot injury on a short week.